The key pathophysiological downstream effect of GBA mutations is decreased glucocerebrosidase (GCase) activity and lysosomal dysfunction and experimental studies have shown a reciprocal relationship of GCase activity and -synuclein aggregation [191, 192]
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Carvedilol can relieve AKI caused by renal IRI and quercetin restores renal function by reducing inflammation (Rezk et al., 2021)
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Spermatogenesis is influenced by various factors or harmful substances and in which multiple signaling pathways are involved [5,6,7]